human ARD1A shRNA silencing AAV

Name
AAV-h-ARD1A-shRNA

Cat No
shAAV-201259

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human NAA10.

shAAV-201259

AAV-h-ARD1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NAA10 (N(alpha)-acetyltransferase 10, NatA catalytic subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ARD1; ARD1A; ARD1P; DXS707; MCOPS1; NATD; OGDNS; TE2

Description (Vector)

N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants.

Gene ID

8260

Gene Name (Vector)

N(alpha)-acetyltransferase 10, NatA catalytic subunit

Gene Symbol

NAA10

HGNC ID

HGNC:18704

ORF Size (aa)

708

RefSeq ID

NM_003491

RefSeq Synonyms

NM_003491, NM_001256120, NM_001256119, BC063377, BC019312, BC000308,

Species

human

UniGene ID

Hs.433291

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.