human APPBP2 shRNA silencing AAV

Name 
AAV-h-APPBP2-shRNA
Cat No 
shAAV-201222
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human APPBP2.

shAAV-201222
AAV-h-APPBP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human APPBP2 (amyloid beta precursor protein binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APP-BP2; HS.84084; PAT1
Description (Vector)
APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.
Gene ID
10513
Gene Name (Vector)
amyloid beta precursor protein binding protein 2
Gene Symbol
APPBP2
HGNC ID
HGNC:622
ORF Size (aa)
1758
ORF Size (bp)
1758 bp
RefSeq ID
NM_006380
RefSeq Synonyms
NM_006380, NM_001282476, BC018121,
Species
human
UniGene ID
Hs.84084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.