human AP4B1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AP4B1.
shAAV-201108
AAV-h-AP4B1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AP4B1 (adaptor related protein complex 4 beta 1 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BETA-4; CPSQ5; SPG47
Description (Vector)
AP4B1 encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
10717
Gene Name (Vector)
adaptor related protein complex 4 beta 1 subunit
Gene Symbol
AP4B1
HGNC ID
HGNC:572
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
RefSeq ID
NM_006594
RefSeq Synonyms
NM_006594, NM_001308312, NM_001253853, NM_001253852, BC014146,
Species
human
UniGene ID
Hs.515048
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.