human AP3D1 shRNA silencing AAV

Name
AAV-h-AP3D1-shRNA

Cat No
shAAV-201100

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human AP3D1.

shAAV-201100

AAV-h-AP3D1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AP3D1 (adaptor related protein complex 3 delta 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADTD; hBLVR; HPS10

Description (Vector)

AP3D1 is a subunit of the AP3 adaptor-like complex, which is not clathrin-associated, but is associated with the golgi region, as well as more peripheral structures. The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and may be directly involved in trafficking to lysosomes. This subunit is implicated in intracellular biogenesis and trafficking of pigment granules, and possibly platelet dense granules and neurotransmitter vesicles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

8943

Gene Name (Vector)

adaptor related protein complex 3 delta 1 subunit

Gene Symbol

AP3D1

HGNC ID

HGNC:568

ORF Size (aa)

2229

ORF Size (bp)

2229 bp

RefSeq ID

NM_003938

RefSeq Synonyms

NM_003938, NM_001261826, NM_001077523, BC010065,

Species

human

UniGene ID

Hs.512815

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.