human AP1G2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AP1G2.
shAAV-201075
AAV-h-AP1G2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AP1G2 (adaptor related protein complex 1 gamma 2 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
G2AD
Description (Vector)
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. There are two alternatively spliced transcript variants of this gene encoding the same protein.
Gene ID
8906
Gene Name (Vector)
adaptor related protein complex 1 gamma 2 subunit
Gene Symbol
AP1G2
HGNC ID
HGNC:556
ORF Size (aa)
1923
ORF Size (bp)
1923 bp
RefSeq ID
NM_003917
RefSeq Synonyms
NM_003917, NM_001282475, NM_001282474, BC051833,
Species
human
UniGene ID
Hs.343244
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.