human ANO6 shRNA silencing AAV

Name 
AAV-h-ANO6-shRNA
Cat No 
shAAV-201022
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ANO6.

shAAV-201022
AAV-h-ANO6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ANO6 (anoctamin 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BDPLT7; SCTS; TMEM16F
Description (Vector)
ANO6 encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
196527
Gene Name (Vector)
anoctamin 6
Gene Symbol
ANO6
HGNC ID
HGNC:25240
ORF Size (aa)
2796
ORF Size (bp)
2796 bp
RefSeq ID
NM_001025356
RefSeq Synonyms
NM_001204803, NM_001142680, NM_001142679, NM_001142678, NM_001025356, BC136445, BC098410,
Species
human
UniGene ID
Hs.696326

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Ad-h-ANO6-shRNA

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.