human ANKK1 shRNA silencing AAV

Name
AAV-h-ANKK1-shRNA

Cat No
shAAV-200934

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ANKK1.

shAAV-200934

AAV-h-ANKK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ANKK1 (ankyrin repeat and kinase domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PKK2

Description (Vector)

ANKK1 belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.

Gene ID

255239

Gene Name (Vector)

ankyrin repeat and kinase domain containing 1

Gene Symbol

ANKK1

HGNC ID

HGNC:21027

ORF Size (aa)

2298

ORF Size (bp)

2298 bp

RefSeq ID

NM_178510

RefSeq Synonyms

NM_178510, BC172460, BC156146,

Species

human

UniGene ID

Hs.448473

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.