human ANGPT2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ANGPT2.
shAAV-200909
AAV-h-ANGPT2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ANGPT2 (angiopoietin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGPT2; ANG2
Description (Vector)
ANGPT2 is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
Gene ID
285
Gene Name (Vector)
angiopoietin 2
Gene Symbol
ANGPT2
HGNC ID
HGNC:485
ORF Size (aa)
1491
ORF Size (bp)
1491 bp
RefSeq ID
NM_001147
RefSeq Synonyms
NM_001147, NM_001118888, NM_001118887, BC143902, BC126202, BC126200,
Species
human
UniGene ID
Hs.583870
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.