human ALDH1L2 shRNA silencing AAV

Name 
AAV-h-ALDH1L2-shRNA
Cat No 
shAAV-200731
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ALDH1L2.

shAAV-200731
AAV-h-ALDH1L2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ALDH1L2 (aldehyde dehydrogenase 1 family member L2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
mtFDH
Description (Vector)
ALDH1L2 encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
Gene ID
160428
Gene Name (Vector)
aldehyde dehydrogenase 1 family member L2
Gene Symbol
ALDH1L2
HGNC ID
HGNC:26777
ORF Size (aa)
2772
ORF Size (bp)
2772 bp
RefSeq ID
NM_001034173
RefSeq Synonyms
NM_001034173, BC103935, BC103934,
Species
human
UniGene ID
Hs.42572

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.