human AKAP3 shRNA silencing AAV

Name
AAV-h-AKAP3-shRNA

Cat No
shAAV-200657

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AKAP3.

shAAV-200657

AAV-h-AKAP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AKAP3 (A-kinase anchoring protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AKAP 110; AKAP110; CT82; FSP95; HEL159; PRKA3; SOB1

Description (Vector)

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.

Gene ID

10566

Gene Name (Vector)

A-kinase anchoring protein 3

Gene Symbol

AKAP3

HGNC ID

HGNC:373

ORF Size (aa)

2562

ORF Size (bp)

2562 bp

RefSeq ID

NM_006422

RefSeq Synonyms

NM_006422, NM_001278309, BC047535,

Species

human

UniGene ID

Hs.98397

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.