human AKAP14 shRNA silencing AAV

Name
AAV-h-AKAP14-shRNA

Cat No
shAAV-200656

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AKAP14.

shAAV-200656

AAV-h-AKAP14-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AKAP14 (A-kinase anchoring protein 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AKAP28; PRKA14

Description (Vector)

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene ID

158798

Gene Name (Vector)

A-kinase anchoring protein 14

Gene Symbol

AKAP14

HGNC ID

HGNC:24061

ORF Size (aa)

594

RefSeq ID

NM_178813

RefSeq Synonyms

NM_178813, NM_001008535, NM_001008534, BC066357,

Species

human

UniGene ID

Hs.592245

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.