human AKAP11 shRNA silencing AAV

Name 
AAV-h-AKAP11-shRNA
Cat No 
shAAV-200652
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AKAP11.

shAAV-200652
AAV-h-AKAP11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AKAP11 (A-kinase anchoring protein 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AKAP-11; AKAP220; PPP1R44; PRKA11
Description (Vector)
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function.
Gene ID
11215
Gene Name (Vector)
A-kinase anchoring protein 11
Gene Symbol
AKAP11
HGNC ID
HGNC:369
ORF Size (aa)
5706
ORF Size (bp)
5706 bp
RefSeq ID
NM_016248
RefSeq Synonyms
NM_016248, BC172498, BC156135,
Species
human
UniGene ID
Hs.105105

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.