human AK3L1 shRNA silencing AAV

Name
AAV-h-AK3L1-shRNA

Cat No
shAAV-200640

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human AK4.

shAAV-200640

AAV-h-AK3L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AK4 (adenylate kinase 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AK 4; AK3; AK3L1; AK3L2

Description (Vector)

AK4 encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.

Gene ID

205

Gene Name (Vector)

adenylate kinase 4

Gene Symbol

AK4

HGNC ID

HGNC:363

ORF Size (aa)

672

ORF Size (bp)

672 bp

RefSeq ID

NM_013410

RefSeq Synonyms

NM_203464, NM_013410, NM_001330616, NM_001005353, BC148270, BC146653, BC136887, BC136886, BC066944, BC040224, BC016180,

Species

human

UniGene ID

Hs.592601

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.