human AHR shRNA silencing AAV

Name 
AAV-h-AHR-shRNA
Cat No 
shAAV-200609
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AHR.

shAAV-200609
AAV-h-AHR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AHR (aryl hydrocarbon receptor). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ah receptor; AhR; AH-receptor; aromatic hydrocarbon receptor; aryl hydrocarbon receptor; bHLHe76; class E basic helix-loop-helix protein 76
Description (eCommerce)
AHR is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, AHR is sequestered in the cytoplasm; upon ligand binding, the protein moves to the nucleus and stimulates transcription of target genes. [taken from NCBI Entrez Gene (Gene ID: 196)].
Description (Vector)
AHR encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons.
Gene ID
196
Gene Name (eCommerce)
aryl hydrocarbon receptor
Gene Name (Vector)
aryl hydrocarbon receptor
Gene Symbol
AHR
HGNC ID
HGNC:348
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2547
ORF Size (bp)
2547 bp
Protein Name (eCommerce)
Aryl hydrocarbon receptor
RefSeq ID
NM_001621
RefSeq Synonyms
NM_001621, BC070080, BC069390,
Research Areas
Apoptosis,Breast Cancer,Cancer,Cell Cycle,Gene Expression,Immunology,RNA Binding,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,immunology
Species
human
Target Sentence
AHR is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. AHR has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, AHR is sequestered in the cytoplasm; upon ligand binding, the protein moves to the nucleus and stimulates transcription of target genes. [taken from NCBI Entrez Gene (Gene ID: 196)].
UniGene ID
Hs.171189
UniProt ID (eCommerce)
P35869

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.