human AGGF1 shRNA silencing AAV

Name 
AAV-h-AGGF1-shRNA
Cat No 
shAAV-200559
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AGGF1.

shAAV-200559
AAV-h-AGGF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AGGF1 (angiogenic factor with G-patch and FHA domains 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
angiogenic factor VG5Q; angiogenic factor with G patch and FHA domains 1; G patch domain-containing protein 7; GPATC7; GPATCH7; HSU84971; HUS84971; hVG5Q; vasculogenesis gene on 5q protein; VG5Q
Description (eCommerce)
Angiogenic factor with G patch and FHA domains 1 (AGGF1) is an angiogenic factor that promotes proliferation of endothelial cells. Mutations in the AFFG1 gene are associated with a susceptibility to Klippel-Trenaunay syndrome [taken from NCBI Entrez Gene (Gene ID: 55109)].
Description (Vector)
AGGF1 encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.
Gene ID
55109
Gene Name (eCommerce)
angiogenic factor with G-patch and FHA domains 1
Gene Name (Vector)
angiogenic factor with G-patch and FHA domains 1
Gene Symbol
AGGF1
HGNC ID
HGNC:24684
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2145
ORF Size (bp)
2145 bp
Protein Name (eCommerce)
Angiogenic factor with G patch and FHA domains 1
RefSeq ID
NM_018046
RefSeq Synonyms
NM_018046, BC032844, BC002828,
Research Areas
Angiogenesis,Cardiovascular,RNA Processing
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
Angiogenic factor with G patch and FHA domains 1 (AGGF1) is an angiogenic factor that promotes proliferation of endothelial cells. Mutations in the AFFG1 gene are associated with a susceptibility to Klippel-Trenaunay syndrome [taken from NCBI Entrez Gene (Gene ID: 55109)].
UniGene ID
Hs.634849
UniProt ID (eCommerce)
Q8N302

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.