human AES shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AES.
shAAV-200523
AAV-h-AES-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AES (amino-terminal enhancer of split). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AES-1; AES-2; ESP1; GRG; Grg-5; GRG5; TLE5
Description (Vector)
AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
166
Gene Name (Vector)
amino-terminal enhancer of split
Gene Symbol
AES
HGNC ID
HGNC:307
ORF Size (aa)
795
ORF Size (bp)
795 bp
RefSeq ID
NM_001130
RefSeq Synonyms
NM_198970, NM_198969, NM_001130, BC113737, BC113735,
Species
human
UniGene ID
Hs.515053
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.