human ADH1A shRNA silencing AAV

Name 
AAV-h-ADH1A-shRNA
Cat No 
shAAV-200446
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ADH1A.

shAAV-200446
AAV-h-ADH1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ADH1
Description (Vector)
ADH1A encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. ADH1A is active in the liver in early fetal life but only weakly active in adult liver. ADH1A is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
Gene ID
124
Gene Name (Vector)
alcohol dehydrogenase 1A (class I), alpha polypeptide
Gene Symbol
ADH1A
HGNC ID
HGNC:249
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_000667
RefSeq Synonyms
NM_000667, BC126306, BC117442, BC074738,
Species
human
UniGene ID
Hs.654433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.