human ADCY4 shRNA silencing AAV

Cat. No: shAAV-200426

Availability: 4-5 weeks

Name: AAV-h-ADCY4-shRNA

This is an AAV expressing shRNA for silencing of Human ADCY4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ADCY4
Gene Name: adenylate cyclase 4
Gene ID: 196883
Gene Synonyms: AC4
ORF Size: 3234 bp
RefSeq#: NM_139247
Gene Description: ADCY4 encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.
UniGene ID: Hs.443428
HGNC ID: HGNC:235