human SCAMP4 shRNA silencing AAV

Cat. No: shAAV-200411

Availability: 4-5 weeks

Name: AAV-h-SCAMP4-shRNA

This is an AAV expressing shRNA for silencing of Human SCAMP4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SCAMP4
Gene Name: secretory carrier membrane protein 4
Gene ID: 113178
Gene Synonyms: SCAMP-4
ORF Size: 690 bp
RefSeq#: NM_079834
Gene Description: Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 (PubMed 11050114)).(supplied by OMIM, Feb 2011)
UniGene ID: Hs.144980
HGNC ID: HGNC:30385