human ADAM33 shRNA silencing AAV

Name
AAV-h-ADAM33-shRNA

Cat No
shAAV-200368

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ADAM33.

shAAV-200368

AAV-h-ADAM33-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADAM33 (ADAM metallopeptidase domain 33). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C20orf153; DJ964F7.1

Description (Vector)

ADAM33 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Gene ID

80332

Gene Name (Vector)

ADAM metallopeptidase domain 33

Gene Symbol

ADAM33

HGNC ID

HGNC:15478

ORF Size (aa)

2079

ORF Size (bp)

2079 bp

RefSeq ID

NM_025220

RefSeq Synonyms

NM_153202, NM_025220, NM_001282447, BC125113, BC062663,

Species

human

UniGene ID

Hs.173716

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.