human ACE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ACE.
shAAV-200182
AAV-h-ACE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ACE (angiotensin I converting enzyme). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACE1; CD143; DCP; DCP1
Description (Vector)
ACE encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
Gene ID
1636
Gene Name (Vector)
angiotensin I converting enzyme
Gene Symbol
ACE
HGNC ID
HGNC:2707
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
RefSeq ID
NM_000789
RefSeq Synonyms
NM_152830, NM_001178057, NM_000789, BC036375,
Species
human
UniGene ID
Hs.654434
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.