human ABP1 shRNA silencing AAV

Name
AAV-h-ABP1-shRNA

Cat No
shAAV-200134

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AOC1.

shAAV-200134

AAV-h-ABP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AOC1 (amine oxidase, copper containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABP; ABP1; DAO; DAO1; KAO

Description (Vector)

ABP1 encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Gene ID

Gene Name (Vector)

amine oxidase, copper containing 1

Gene Symbol

AOC1

HGNC ID

HGNC:80

ORF Size (aa)

2256

ORF Size (bp)

2256 bp

RefSeq ID

NM_001091

RefSeq Synonyms

NM_001272072, NM_001091, BC014093,

Species

human

UniGene ID

Hs.647097

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.