human ABCG1 shRNA silencing AAV

Name
AAV-h-ABCG1-shRNA

Cat No
shAAV-200097

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ABCG1.

shAAV-200097

AAV-h-ABCG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABCG1 (ATP binding cassette subfamily G member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABC8; WHITE1

Description (Vector)

ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.

Gene ID

9619

Gene Name (Vector)

ATP binding cassette subfamily G member 1

Gene Symbol

ABCG1

HGNC ID

HGNC:73

ORF Size (aa)

2001

ORF Size (bp)

2001 bp

RefSeq ID

NM_004915

RefSeq Synonyms

NM_207629, NM_207628, NM_207627, NM_207174, NM_016818, NM_004915, BC029158,

Species

human

UniGene ID

Hs.124649

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.