human ABCB8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ABCB8.
shAAV-200065
AAV-h-ABCB8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ABCB8 (ATP binding cassette subfamily B member 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EST328128; M-ABC1; MABC1
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Gene ID
11194
Gene Name (Vector)
ATP binding cassette subfamily B member 8
Gene Symbol
ABCB8
HGNC ID
HGNC:49
ORF Size (aa)
2157
ORF Size (bp)
2157 bp
RefSeq ID
NM_007188
RefSeq Synonyms
NM_007188, NM_001282293, NM_001282292, NM_001282291, BC151235, BC146829, BC143080, BC141836, BC141814,
Species
human
UniGene ID
Hs.647118
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.