human ABCB6 shRNA silencing AAV

Name 
AAV-h-ABCB6-shRNA
Cat No 
shAAV-200061
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ABCB6.

shAAV-200061
AAV-h-ABCB6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABCB6 (ATP binding cassette subfamily B member 6 (Langereis blood group)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ABC; ABC14; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; umat
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Gene ID
10058
Gene Name (Vector)
ATP binding cassette subfamily B member 6 (Langereis blood group)
Gene Symbol
ABCB6
HGNC ID
HGNC:47
ORF Size (aa)
2529
ORF Size (bp)
2529 bp
RefSeq ID
NM_005689
RefSeq Synonyms
NM_005689, BC000559,
Species
human
UniGene ID
Hs.107911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.