human AASDHPPT shRNA silencing AAV

Name 
AAV-h-AASDHPPT-shRNA
Cat No 
shAAV-200034
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AASDHPPT.

shAAV-200034
AAV-h-AASDHPPT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AASD-PPT; ACPS; CGI-80; LYS2; LYS5
Description (Vector)
AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Gene ID
60496
Gene Name (Vector)
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Gene Symbol
AASDHPPT
HGNC ID
HGNC:14235
ORF Size (aa)
930
ORF Size (bp)
930 bp
RefSeq ID
NM_015423
RefSeq Synonyms
NM_015423, BC016728, BC015470,
Species
human
UniGene ID
Hs.524009

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.