human A4GALT shRNA silencing AAV

Name
AAV-h-A4GALT-shRNA

Cat No
shAAV-200008

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human A4GALT.

shAAV-200008

AAV-h-A4GALT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human A4GALT (alpha 1,4-galactosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A14GALT; A4GALT1; Gb3S; P(k); P1; P1PK; PK

Description (Vector)

A4GALT catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.

Gene ID

53947

Gene Name (Vector)

alpha 1,4-galactosyltransferase

Gene Symbol

A4GALT

HGNC ID

HGNC:18149

ORF Size (aa)

1062

ORF Size (bp)

1062 bp

RefSeq ID

NM_017436

RefSeq Synonyms

NM_017436, NM_001318038, BC055286, BC017068,

Species

human

UniGene ID

Hs.105956

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.