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rat PIM3 Adenovirus

Name 
Ad-r-PIM3
Cat No 
ADV-294590
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Rat Pim3.

ADV-294590
Ad-r-PIM3

Ready-to-use Adenovirus expressing Rat Pim3 (Pim-3 proto-oncogene, serine/threonine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
Gene ID
64534
Gene Name (Vector)
Pim-3 proto-oncogene, serine/threonine kinase
Gene Symbol
Pim3
ORF Size (aa)
981
ORF Size (bp)
981 bp
RefSeq ID
NM_022602
RefSeq Synonyms
NM_022602, BC097317,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.