rat PELP1 Adenovirus
This is an Adenovirus expressing Rat Pelp1.
ADV-294185
Ad-r-PELP1
Ready-to-use Adenovirus expressing Rat Pelp1 (proline, glutamate and leucine rich protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RGD1306320
Description (Vector)
Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1. May have important functional implications in ER/growth factor cross-talk. Interacts with several growth factor signaling components including EGFR and HRS. Involved in nuclear receptor signaling via its interaction with AR and NR3C1. May promote tumorigenesis via its interaction with and modulation of several oncogenes including SRC, PI3K, STAT3 and EGFR. Plays a role in cancer cell metastasis via its ability to modulate E2-mediated cytoskeleton changes and cell migration via its interaction with SRC and PI3K.
Gene ID
360552
Gene Name (Vector)
proline, glutamate and leucine rich protein 1
Gene Symbol
Pelp1
ORF Size (aa)
3393
ORF Size (bp)
3393 bp
RefSeq ID
NM_001024270
RefSeq Synonyms
NM_001024270, BC101890,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.