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rat NR1H4 Adenovirus

Name 
Ad-r-NR1H4
Cat No 
ADV-293596
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Rat Nr1h4.

ADV-293596
Ad-r-NR1H4

Ready-to-use Adenovirus expressing Rat Nr1h4 (nuclear receptor subfamily 1, group H, member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Fxr
Description (Vector)
Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
Gene ID
60351
Gene Name (Vector)
nuclear receptor subfamily 1, group H, member 4
Gene Symbol
Nr1h4
ORF Size (aa)
1452
ORF Size (bp)
1452 bp
RefSeq ID
NM_021745
RefSeq Synonyms
NM_021745, BC083815,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.