rat PLEKHF1 Adenovirus

Name 
Ad-r-PLEKHF1
Cat No 
ADV-291773
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Arhgap22.

ADV-291773
Ad-r-PLEKHF1

Ready-to-use Adenovirus expressing Rat Plekhf1 (pleckstrin homology and FYVE domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Gene ID
308543
Gene Name (Vector)
pleckstrin homology and FYVE domain containing 1
Gene Symbol
Plekhf1
ORF Size (aa)
840
RefSeq ID
NM_001013148
RefSeq Synonyms
NM_001013148, BC079354,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.