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rat CYR61 Adenovirus

Name 
Ad-r-CYR61
Cat No 
ADV-291493
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Rat Cyr61.

ADV-291493
Ad-r-CYR61

Ready-to-use Adenovirus expressing Rat Cyr61 (cysteine-rich, angiogenic inducer, 61). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Gene ID
83476
Gene Name (Vector)
cysteine-rich, angiogenic inducer, 61
Gene Symbol
Cyr61
ORF Size (aa)
1140
ORF Size (bp)
1140 bp
RefSeq ID
NM_031327
RefSeq Synonyms
NM_031327, BC081689,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.