rat WDR79 Adenovirus
This is an Adenovirus expressing Rat Wrap53.
ADV-291353
Ad-r-WDR79
Ready-to-use Adenovirus expressing Rat Wrap53 (WD repeat containing, antisense to TP53). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Wdr79
Description (Vector)
Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
Gene ID
287432
Gene Name (Vector)
WD repeat containing, antisense to TP53
Gene Symbol
Wrap53
ORF Size (aa)
1599
ORF Size (bp)
1599 bp
RefSeq ID
NM_001007610
RefSeq Synonyms
NM_001007610, BC083696,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.