rat MAP3K11 Adenovirus

Name
Ad-r-MAP3K11

Cat No
ADV-290751

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Adssl1.

ADV-290751

Ad-r-MAP3K11

Ready-to-use Adenovirus expressing Rat Map3k11 (mitogen-activated protein kinase kinase kinase 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Mlk-3; Mlk3; RHOE

Description (Vector)

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Gene ID

309168

Gene Name (Vector)

mitogen-activated protein kinase kinase kinase 11

Gene Symbol

Map3k11

ORF Size (aa)

2553

ORF Size (bp)

2553 bp

RefSeq ID

NM_001013150

RefSeq Synonyms

NM_001013150, BC081952,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.