rat ILK Adenovirus

Name
Ad-r-ILK

Cat No
ADV-290524

Availability
4-5 weeks

This is an Adenovirus expressing Rat Ilk.

ADV-290524

Ad-r-ILK

Ready-to-use Adenovirus expressing Rat Ilk (integrin-linked kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)

Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Gene ID

170922

Gene Name (Vector)

integrin-linked kinase

Gene Symbol

Ilk

ORF Size (aa)

1359

ORF Size (bp)

1359 bp

RefSeq ID

NM_133409

RefSeq Synonyms

NM_133409, BC062406,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.