mouse PSTPIP1 Adenovirus

Name
Ad-m-PSTPIP1

Cat No
ADV-281019

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Pstpip1.

ADV-281019

Ad-m-PSTPIP1

Ready-to-use Adenovirus expressing Mouse Pstpip1 (proline-serine-threonine phosphatase-interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CD2BP1; def-2

Description (Vector)

Involved in regulation of the actin cytoskeleton. May regulate the WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to the ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allows PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation (By similarity). Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2.

Gene ID

19200

Gene Name (Vector)

proline-serine-threonine phosphatase-interacting protein 1

Gene Symbol

Pstpip1

ORF Size (aa)

1248

ORF Size (bp)

1248 bp

RefSeq ID

NM_011193

RefSeq Synonyms

NM_011193, BC096761,

Species

mouse

UniGene ID

Mm.2534

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.