mouse LIN7C Adenovirus
This is an Adenovirus expressing Mouse Lin7c.
ADV-279009
Ad-m-LIN7C
Ready-to-use Adenovirus expressing Mouse Lin7c (lin-7 homolog C (C. elegans)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9130007B12Rik; AI303698; AU019331; AW125731; D2Ertd520e; LIN-7-C; LIN-7C; MALS-3; Veli3
Description (Vector)
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Gene ID
22343
Gene Name (Vector)
lin-7 homolog C (C. elegans)
Gene Symbol
Lin7c
ORF Size (aa)
594
RefSeq ID
NM_011699
RefSeq Synonyms
NM_011699, BC046966,
Species
mouse
UniGene ID
Mm.478053
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.