mouse WWP2 Adenovirus
This is an Adenovirus expressing Mouse Rtp3.
ADV-276354
Ad-m-WWP2
Ready-to-use Adenovirus expressing Mouse Wwp2 (WW domain containing E3 ubiquitin protein ligase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1300010O06Rik; AA690238; AIP2; AW554328
Description (Vector)
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Gene ID
66894
Gene Name (Vector)
WW domain containing E3 ubiquitin protein ligase 2
Gene Symbol
Wwp2
ORF Size (aa)
2613
ORF Size (bp)
2613 bp
RefSeq ID
NM_025830
RefSeq Synonyms
NM_025830, BC048184, BC039921,
Species
mouse
UniGene ID
Mm.390058
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.