mouse WNK1 Adenovirus
This is an Adenovirus expressing Mouse Pradc1.
ADV-276298
Ad-m-WNK1
Ready-to-use Adenovirus expressing Mouse Wnk1 (WNK lysine deficient protein kinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6430573H23Rik; EG406236; Hsn2; mKIAA0344; Prkwnk1
Description (Vector)
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L (By similarity).
Gene ID
232341
Gene Name (Vector)
WNK lysine deficient protein kinase 1
Gene Symbol
Wnk1
ORF Size (aa)
6387
ORF Size (bp)
6387 bp
RefSeq ID
NM_198703
RefSeq Synonyms
NM_198703, NM_001199084, NM_001199083, NM_001185021, NM_001185020, BC171955, BC145282, BC138445,
Species
mouse
UniGene ID
Mm.333349
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.