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mouse TWSG1 Adenovirus

Name 
Ad-m-TWSG1
Cat No 
ADV-275372
Availability
4-5 weeks

This is an Adenovirus expressing Mouse Twsg1.

ADV-275372
Ad-m-TWSG1

Ready-to-use Adenovirus expressing Mouse Twsg1 (twisted gastrulation BMP signaling modulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403e; Tsg; Twg
Description (Vector)
TWSG1 may be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).
Gene ID
65960
Gene Name (Vector)
twisted gastrulation BMP signaling modulator 1
Gene Symbol
Twsg1
ORF Size (aa)
669
RefSeq ID
NM_023053
RefSeq Synonyms
NM_023053, BC004850,
Species
mouse
UniGene ID
Mm.470669

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.