mouse TRPV4 Adenovirus

Name 
Ad-m-TRPV4
Cat No 
ADV-275109
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Trpv4.

ADV-275109
Ad-m-TRPV4

Ready-to-use Adenovirus expressing Mouse Trpv4 (transient receptor potential cation channel, subfamily V, member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
0610033B08Rik; OTRPC4; Trp12; VR-OAC; VRL-2; VROAC
Description (Vector)
Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.
Gene ID
63873
Gene Name (Vector)
transient receptor potential cation channel, subfamily V, member 4
Gene Symbol
Trpv4
ORF Size (aa)
2616
ORF Size (bp)
2616 bp
RefSeq ID
NM_022017
RefSeq Synonyms
NM_022017, BC127052,
Species
mouse
UniGene ID
Mm.266450

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.