mouse TNPO2 Adenovirus
This is an Adenovirus expressing Mouse Tnpo2.
ADV-274776
Ad-m-TNPO2
Ready-to-use Adenovirus expressing Mouse Tnpo2 (transportin 2 (importin 3, karyopherin beta 2b)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110034O24Rik; AA414969; AI464345; AI852433; IPO3; Knpb2b; Kpnb2b; TRN2
Description (Vector)
Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).
Gene ID
212999
Gene Name (Vector)
transportin 2 (importin 3, karyopherin beta 2b)
Gene Symbol
Tnpo2
ORF Size (aa)
2664
ORF Size (bp)
2664 bp
RefSeq ID
NM_145390
RefSeq Synonyms
NM_145390, NM_001122843, BC003275,
Species
mouse
UniGene ID
Mm.220357
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.