mouse TNKS Adenovirus
This is an Adenovirus expressing Mouse Tnks.
ADV-274752
Ad-m-TNKS
Ready-to-use Adenovirus expressing Mouse Tnks (tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930554K12Rik; AI662855; ARTD5; C86528; D130072O21Rik; mTNKS1; TANK1
Description (Vector)
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles.
Gene ID
21951
Gene Name (Vector)
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Gene Symbol
Tnks
ORF Size (aa)
3963
ORF Size (bp)
3963 bp
RefSeq ID
NM_175091
RefSeq Synonyms
NM_175091, BC057370,
Species
mouse
UniGene ID
Mm.88364
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.