mouse TNIK Adenovirus
This is an Adenovirus expressing Mouse Tnik.
ADV-274743
Ad-m-TNIK
Ready-to-use Adenovirus expressing Mouse Tnik (TRAF2 and NCK interacting kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1500031A17Rik; 4831440I19Rik; AI451411; C530008O15Rik; C630040K21Rik
Description (Vector)
Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
Gene ID
665113
Gene Name (Vector)
TRAF2 and NCK interacting kinase
Gene Symbol
Tnik
ORF Size (aa)
4092
ORF Size (bp)
4092 bp
RefSeq ID
NM_001163007
RefSeq Synonyms
NM_026910, NM_001163009, NM_001163008, NM_001163007, BC158059, BC158011, BC151003, BC137800, BC137799,
Species
mouse
UniGene ID
Mm.126193
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.