mouse C3 Adenovirus

Name
Ad-m-C3

Cat No
ADV-274727

Availability
4-5 weeks

This is an Adenovirus expressing Mouse C3.

ADV-274727

Ad-m-C3

Ready-to-use Adenovirus expressing Mouse C3 (complement component 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI255234; ASP; HSE-MSF; Plp

Description (Vector)

C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates|Function: Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Gene ID

12266

Gene Name (Vector)

complement component 3

Gene Symbol

ORF Size (aa)

4992

ORF Size (bp)

4992 bp

RefSeq ID

NM_009778

RefSeq Synonyms

NM_009778, BC043338,

Species

mouse

UniGene ID

Mm.19131

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.