mouse TIMELESS Adenovirus

Name
Ad-m-TIMELESS

Cat No
ADV-274213

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Timeless.

ADV-274213

Ad-m-TIMELESS

Ready-to-use Adenovirus expressing Mouse Timeless (timeless circadian clock 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

C77407; Debt69; tim

Description (Vector)

Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

Gene ID

21853

Gene Name (Vector)

timeless circadian clock 1

Gene Symbol

Timeless

ORF Size (aa)

3591

ORF Size (bp)

3591 bp

RefSeq ID

NM_011589

RefSeq Synonyms

NM_011589, NM_001164081, NM_001164080, NM_001136082, BC082770, BC058641,

Species

mouse

UniGene ID

Mm.6458

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.