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mouse THOC7 Adenovirus

Name 
Ad-m-THOC7
Cat No 
ADV-274169
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse THOC7.

ADV-274169
Ad-m-THOC7

Ready-to-use Adenovirus expressing Mouse THOC7 (THO complex 7 homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1500006O09Rik; 9230101K24Rik; MGC151296; MGC151322; Nif3l1bp1;
Description (Vector)
Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.
Gene ID
66231
Gene Name (Vector)
THO complex 7 homolog (Drosophila)
Gene Symbol
THOC7
ORF Size (aa)
615
ORF Size (bp)
615 bp
RefSeq ID
NM_025435
RefSeq Synonyms
NM_025435, NM_001285780, NM_001013578, BC116945, BC116919, BC054419,
Species
mouse
UniGene ID
Mm.295875

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.