mouse SYTL2 Adenovirus

Name
Ad-m-SYTL2

Cat No
ADV-273575

Availability
4-5 weeks

This is an Adenovirus expressing Mouse SYTL2.

ADV-273575

Ad-m-SYTL2

Ready-to-use Adenovirus expressing Mouse SYTL2 (synaptotagmin-like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI266830; mKIAA1597; Slp2

Description (Vector)

Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.

Gene ID

83671

Gene Name (Vector)

synaptotagmin-like 2

Gene Symbol

SYTL2

ORF Size (aa)

2853

ORF Size (bp)

2853 bp

RefSeq ID

NM_031394

RefSeq Synonyms

NM_031394, NM_001289586, NM_001289585, NM_001289584, NM_001289583, NM_001040088, NM_001040087, NM_001040086, NM_001040085, BC145398, BC138714,

Species

mouse

UniGene ID

Mm.26751

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.