mouse SMC6 Adenovirus

Name 
Ad-m-SMC6
Cat No 
ADV-272634
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Mouse Smc6.

ADV-272634
Ad-m-SMC6

Ready-to-use Adenovirus expressing Mouse Smc6 (structural maintenance of chromosomes 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; mKIAA4103; SMC-6; Smc6l1
Description (Vector)
Core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). Required for recruitment of telomeres to PML nuclear bodies.
Gene ID
67241
Gene Name (Vector)
structural maintenance of chromosomes 6
Gene Symbol
Smc6
ORF Size (aa)
3294
ORF Size (bp)
3294 bp
RefSeq ID
NM_025695
RefSeq Synonyms
NM_025695, NM_001324476, BC090630,
Species
mouse
UniGene ID
Mm.173953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.