mouse ROCK2 Adenovirus
This is an Adenovirus expressing Mouse Rock2.
ADV-270780
Ad-m-ROCK2
Ready-to-use Adenovirus expressing Mouse Rock2 (Rho-associated coiled-coil containing protein kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B230113H15Rik; mKIAA0619; Rho-kinase; Rock-II; Rock2m; ROKalpha
Description (Vector)
Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus.
Gene ID
19878
Gene Name (Vector)
Rho-associated coiled-coil containing protein kinase 2
Gene Symbol
Rock2
ORF Size (aa)
4164
ORF Size (bp)
4164 bp
RefSeq ID
NM_009072
RefSeq Synonyms
NM_009072, BC157053, BC156153,
Species
mouse
UniGene ID
Mm.276024
Recently Viewed Products
AAV-m-CCND3-shRNA
Cat No: shAAV-254862
Ad-m-KYNU-shRNA
Cat No: shADV-263210
Ad-m-ETHE1-shRNA
Cat No: shADV-258732
AAV-m-SLC24A4-shRNA
Cat No: shAAV-272179
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.